The permeability of muscle capillaries to horseradish peroxidase.

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The permeability of muscle capillaries to horseradish peroxidase

The main objective of this study was to determine the pathways by which horseradish peroxidase (HRP) can cross the endothelium of muscle capillaries. Specimens of mouse diaphragm were fixed for cytochemical analysis at various intervals after intervenous injection of 0.5 mg HRP, at 4 min after intervenous injection of varied amounts of HRP, and at 4 min after intervenous injections in various ...

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In this study we attempted to identify a morphologic counterpart of the small pore of muscle capillaries. The existence of such a pore has been postulated by physiologists to explain the permeability of muscle capillaries to small macromolecules. We injected mice intravenously with microperoxidase (MP) and fixed specimens of diaphragm at intervals of 0-250 s after the injection to localize the ...

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 1975

ISSN: 0021-9525,1540-8140

DOI: 10.1083/jcb.66.3.531